Uncompressed MKV?

I have created my AVS file, in which I use AvsPmod to do all my editing.


LoadPlugin("F:\-----\Downloads\Encoding Software\MeGUI_2356_x86\tools\dgindex\DGDecode.dll")
DGDecode_mpeg2source("C:\Users\-----\Videos\SAMURAI SHAMPLOO V1 E1.d2v", cpu=6, info=3)
LoadPlugin("F:\-----\Downloads\Encoding Software\MeGUI_2356_x86\tools\avisynth_plugin\Colo rMatrix.dll")
ColorMatrix(hints=true, interlaced=true, threads=0)
Load_Stdcall_Plugin("F:\-----\Downloads\Encoding Software\MeGUI_2356_x86\tools\yadif\yadif.dll")
Yadif(order=1)
crop(2, 6, -2, -4)
Lanczos4Resize(1024,576)
LoadPlugin("C:\Program Files (x86)\AviSynth 2.5\plugins\TTempSmooth.dll")
TTempSmooth()
Import("C:\Program Files (x86)\AviSynth 2.5\plugins\LSFmod.v1.9.avsi")
LSFmod(strength=120)
LoadPlugin("C:\Program Files (x86)\AviSynth 2.5\plugins\gradfun2db.dll")
gradfun2dbmod(thr=3,str=0,mask=false)



So how the above AVS file looks in AvsPmod, is exactly how I want the video to look. I use MeGUI to encode to MKV, but when I encode the video, it seems as though it was pointless even going through the effort of adding filters. I've done so many tests and they all look the same - Watchable, and most people wouldn't complain, but I edited the video for a reason and it's not the result I wanted. My video is anime and the encoder setting is unrestricted 2pass Anime_Toon HQ, but I have tried others. I've played around with a few of settings within the profiles, but I don't seem to have much luck. I understand compression is the reason for this, so if someone can perhaps enlighten me, that would help me heaps. All I am trying to do is keep what I see in AvsPmod and encode with the least amount of quality loss as possible.